Back to Departmental Colloquium: Spring 2010
Departmental Colloquium
Date: Tuesday, Feb 16, 2010
Time: 4:15PM
Location: JWB 335
TUESDAY
Cecilia Diniz Behn
University of Michigan
Title |
Investigating the dynamics of REM sleep |
Abstract |
Microdialysis and microinjection experiments suggest that neurotransmitter dynamics play an important role in the initiation and maintenance of sleep/wake states. However, the synaptic coupling in traditional population firing rate models does not explicitly incorporate the dynamics of neurotransmitter concentrations. We introduce a novel network modeling framework that includes neurotransmitter concentrations, and we use this framework to model interactions among primary brainstem nuclei involved in rat sleep/wake regulation. Analysis of the bifurcation structure underlying model dynamics provides insights into the mechanisms governing REM sleep, particularly those associated with circadian modulation. |
Data Science and Machine Learning
Applied Mathematics